Research activities

At the molecular level, we use optical tweezers and single-molecule fluorescence to study how chaperones fold amino-acid chains into functional proteins, and more recently to probe the role of ribosomes and translation.

At the cellular level, we use time-lapse microscopy and image analysis to understand how multi-cellular systems self-organise, with a specific recent interest in organoids.

The group is based at the AMOLF institute in Amsterdam, and is part of the Living Matter initiative. It is headed by Sander Tans, who is also affiliated with Delft University of Technology, and the Kavli institute of Nanoscience.

If you are interested in joining our team, send us an e-mail to s.tans@amolf.nl

See the Tans group website
  • New algorithm improves ability to track movements of cells in organs

    Read more

  • One rulebook to fold all proteins

    Inside living cells, ribosomes produce roughly five hundred brand-new protein chains every second, and each one must fold into the right 3D shape - or risk disease. New research shows …

    Read more

  • Intestinal surface cells pull rather than push

    Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess …

    Read more

  • OrganoidNL Symposium 2025: Exploring the future of organoid research

    Read more

Read more news articles