Research activities

At the molecular level, we use optical tweezers and single-molecule fluorescence to study how chaperones fold amino-acid chains into functional proteins, and more recently to probe the role of ribosomes and translation.

At the cellular level, we use time-lapse microscopy and image analysis to understand how multi-cellular systems self-organise, with a specific recent interest in organoids.

The group is based at the AMOLF institute in Amsterdam, and is part of the Living Matter initiative. It is headed by Sander Tans, who is also affiliated with Delft University of Technology, and the Kavli institute of Nanoscience.

If you are interested in joining our team, send us an e-mail to s.tans@amolf.nl

See the Tans group website
  • September and October doctorate celebrations

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  • New algorithm improves ability to track movements of cells in organs

    Frustrated by the time cost of manually checking cell tracking data, AMOLF PhD student Max Betjes developed an algorithm to more efficient cell-tracking analysis. He validated this automated analysis on …

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  • One rulebook to fold all proteins

    Inside living cells, ribosomes produce roughly five hundred brand-new protein chains every second, and each one must fold into the right 3D shape - or risk disease. New research shows …

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  • Intestinal surface cells pull rather than push

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