Publications - Quantitative Developmental Biology

M.A. Betjes, R.N.U. Kok, S.J. Tans and J.S. van Zon, Cell tracking with accurate error prediction, Nature Meth., (2025)

D. Krueger, W.K. Spoelstra, D.J. Mastebroek, R.N.U. Kok, S. WU, M. Nikolaev, M. Bannier-Hélaouët, N. Gjorevski, M. Lutolf, J.H. van Es, J.S. van Zon, S.J. Tans and H. Clevers, Epithelial tension controls intestinal cell extrusion, Science 389, (6764), eadr8753: 1-16 (2025)

J.R. Buissant des Amorie, M.A. Betjes, J.H. Bernink, J.H. Hageman, V.E. Geurts, H. Begthel, D. Laskaris, M.C. Heinz, I. Jordens, T. Vinck, R.M. Houtekamer, I. Verlaan-Klink, S.R. Brunner, J. van Rheenen, M. Gloerich, H. Clevers, S.J. Tans, J.S. van Zon and H.J.G. Snippert, Intestinal tuft cell subtypes represent successive stages of maturation driven by crypt-villus signaling gradients, Nat. Commun. 16, (1), 6765 : 1-18 (2025)

B. Demirbas, Stress-induced protein dynamics and growth arrest in C. elegans during development, Leiden University, 2025-05-16

R.N.U. Kok, W.K. Spoelstra, M.A. Betjes, J.S. van Zon and S.J. Tans, Label-free cell imaging and tracking in 3D organoids, Cell Rep. Phys. Sci. 6, (4), 102522: 1-12 (2025)

N.T.B. Nguyen, S. Gevers, R.N.U. Kok, L.M. Burgering, H. Neikes, N. Akkerman, M.A. Betjes, M.C. Ludikhuize, C. Gulersonmez, E.C.A. Stigter, Y. Vercoulen, J. Drost, H. Clevers, M. Vermeulen, J.S. van Zon, S.J. Tans, B.M.T. Burgering and M.J. Rodríguez Colman, Lactate controls cancer stemness and plasticity through epigenetic regulation, Cell Metab. 37, (4), 903-919 (2025)

D. Wang, W.K. Spoelstra, L. Lin, N. Akkerman, D. Krueger, T. Dayton, J.S. van Zon, S.J. Tans, J.H. van Es and H. Clevers, Interferon-responsive intestinal BEST4/CA7+ cells are targets of bacterial diarrheal toxins, Cell Stem Cell 32, (4), 598-612.e5 (2025)

R.N.U. Kok, Homeostasis in intestinal organoids at the single cell level, Delft University of Technology, 2024-04-10

G. Patil and J.S. van Zon, Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing, Curr. Opin. Genet. Dev. 85, 102172: 1-8 (2024)

S. Baglamis, V.M. Sheraton, D. Meijer, H. Qian, R.A. Hoebe, K.J. Lenos, M.A. Betjes, S.J. Tans, J.S. van Zon, L. Vermeulen and P.M. Krawczyk, Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures, Sci. Rep. 13, (1), 18832: 1-13 (2023)