Publications - Quantitative Developmental Biology

W.K. Spoelstra, Shedding light on dynamic processes in the intestinal epithelium, Delft University of Technology, 2026-01-23

B. Demirbas, O. Filina, T. Louisse, A. Natarajan, Y.J. Goos, M.A. Sánchez-Romero, M. Olmedo and J.S. van Zon, Body-wide synchronization of insulin-signaling dependent DAF-16/FOXO nuclear translocation pulses correlated with C. elegans growth, Nat. Commun. 16, (1), 11273: 1-16 (2025)

D. Wang, S. Lim, W.J. van de Wetering, C. Lopez-Iglesias, Y. Okura, Y. Teranishi-Ikawa, A. Mizoroki, W.K. Spoelstra, T. Dayton, G.J.F. van Son, A. Pronk, N. Smakman, G.B.C. Gonera-de Jong, S. Withoff, I.H. Jonkers, J.S. van Zon, S.J. Tans, P.J. Peters, J.H. van Es and H. Clevers, Human gut M cells resemble dendritic cells and present gluten antigen, Nature, (2025)

M.A. Betjes, R.N.U. Kok, S.J. Tans and J.S. van Zon, Cell tracking with accurate error prediction, Nature Meth. 22, 2400-2410 (2025)

D. Krueger, W.K. Spoelstra, D.J. Mastebroek, R.N.U. Kok, S. WU, M. Nikolaev, M. Bannier-Hélaouët, N. Gjorevski, M. Lutolf, J.H. van Es, J.S. van Zon, S.J. Tans and H. Clevers, Epithelial tension controls intestinal cell extrusion, Science 389, (6764), eadr8753: 1-16 (2025)

J.R. Buissant des Amorie, M.A. Betjes, J.H. Bernink, J.H. Hageman, V.E. Geurts, H. Begthel, D. Laskaris, M.C. Heinz, I. Jordens, T. Vinck, R.M. Houtekamer, I. Verlaan-Klink, S.R. Brunner, J. van Rheenen, M. Gloerich, H. Clevers, S.J. Tans, J.S. van Zon and H.J.G. Snippert, Intestinal tuft cell subtypes represent successive stages of maturation driven by crypt-villus signaling gradients, Nat. Commun. 16, (1), 6765 : 1-18 (2025)

B. Demirbas, Stress-induced protein dynamics and growth arrest in C. elegans during development, Leiden University, 2025-05-16

R.N.U. Kok, W.K. Spoelstra, M.A. Betjes, J.S. van Zon and S.J. Tans, Label-free cell imaging and tracking in 3D organoids, Cell Rep. Phys. Sci. 6, (4), 102522: 1-12 (2025)

D. Wang, W.K. Spoelstra, L. Lin, N. Akkerman, D. Krueger, T. Dayton, J.S. van Zon, S.J. Tans, J.H. van Es and H. Clevers, Interferon-responsive intestinal BEST4/CA7+ cells are targets of bacterial diarrheal toxins, Cell Stem Cell 32, (4), 598-612.e5 (2025)

N.T.B. Nguyen, S. Gevers, R.N.U. Kok, L.M. Burgering, H. Neikes, N. Akkerman, M.A. Betjes, M.C. Ludikhuize, C. Gulersonmez, E.C.A. Stigter, Y. Vercoulen, J. Drost, H. Clevers, M. Vermeulen, J.S. van Zon, S.J. Tans, B.M.T. Burgering and M.J. Rodríguez Colman, Lactate controls cancer stemness and plasticity through epigenetic regulation, Cell Metab. 37, (4), 903-919 (2025)