A chiral switch: balancing between equilibrium and non-equilibrium states

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DOI http://dx.doi.org/10.1039/c9cc03250a
Reference I. Baglai, M. Leeman, B. Kaptein, R.M. Kellogg and W.L. Noorduin, A chiral switch: balancing between equilibrium and non-equilibrium states, Chem. Commun. 55, 48: 6910-6913 (2019)
Group Self-Organizing Matter

Herein we introduce a “chiral switch” – a sequence of operations that alternate between equilibrium and non-equilibrium conditions to switch the absolute configuration of a chiral center. The generality and practical potential of the technique are demonstrated with three unnatural α-amino acid precursors.