Topics to be discussed

Microscopy and spectroscopy of materials – Breakout session 1

Several types of microscopy and spectroscopy are being developed and used to enable the detailed study of material systems. Optical microscopy setups are used to look at material surfaces with magnification up to the diffraction limit and obtain spectroscopic information such as reflection/transmission/absorption, (photo)luminescence intensity and lifetime, Raman scattering, and transient absorption. Beyond these standard techniques, we explore nanophotonic systems to achieve super-resolution imaging as well as surface-enhanced Raman spectroscopy and optical analog computing. Complementary, multiple electron microscopes are used for ultra-high resolution imaging, with additional features such as focused-ion beam milling, EBSD, EDX, and beam-blanking. Pioneering research into cathodoluminescence (CL) spectroscopy is ongoing, with a focus on pump-probe laser-electron excitation and the quantum-nature of the electron beam. CL spectroscopy is employed both for the study of nanophotonic and optoelectronic material systems. Finally, we expect a new TEM to be installed in early 2024 with in situ capabilities, such as measuring in liquid and gas environments, and under electrical bias and light excitation.  

Organoid systems and immune biology – Breakout session 2

At AMOLF, we have multiple research teams that employ cutting-edge physics-inspired approaches to study organoid systems and immune biology. Our work relies on techniques such as fluorescence time-lapse microscopy,, single molecule imaging, and quantitative image and data analysis, to study stem cell dynamics, differentiation, cell signaling and immune recognition, with clear technological and therapeutic applications. For example, we have developed deep-learned based approaches to automatically track all cells in growing organoids as they move, divide and differentiate, that we currently use to understand and control at will the differentiation of rate intestinal cell types. In addition, we use hybrid models of immune cell – tumor cell contacts, interfacing live immune cells with synthetic or cell-derived membranes, to study receptor organization and signaling. In reverse, we study how therapeutics need to organize receptors to achieve desired immune cell functions.

Information processing and sensing – Breakout session 3

At AMOLF we have multiple research teams with world-class expertise in the physics of sensing and information. Our work covers areas such as nanoscale light sources, metasurfaces for high-resolution, compact imaging, quantum and thermal noise limited displacement measurements, and passive information processing and event detection for optical and mechanical signals. We have state-of-the art facilities including an in-house nanofabrication cleanroom and advanced microscopy equipment. As example of past successful collaborations with industry, we teamed with ASML/ARCNL to develop smart mechanical metamaterials to improve high precision positioning systems in lithography.

Program

13.30 – 13.45 Welcome, coffee and tea

13.45 – 14.00 Brief Introduction to AMOLF (organization/research/facilities)

14.00 – 14.30 Funding opportunity summary and successful collaboration examples

14.30 – 15.30 Poster sessions on 3 breakout topics (AMOLF students presenting technology)

15.30 – 16.30 Parallel collaboration brainstorm sessions (with company pitches)

– Microscopy and spectroscopy of materials

– Organoid systems and immune biology

– Information processing and sensing

16.30 – 17.30 Drinks & snacks

Contact

Secretary Office AMOLF Industry Day
E-mail: events@amolf.nl

Pictures: Ivar Pel