Research in the Systems Biology group (Group Leader: Tom Shimizu) focuses on developing a physical understanding of biological behavior. We develop in vivo experiments to measure dynamics at multiple spatial and organizational scales, as well as theoretical modeling and data analysis frameworks to connect phenomena across those scales. Primary model organisms are the bacterium E. coli and the nematode C. elegans, with occasional forays into the lives of other creatures.
We have developed a FRET microscopy method that allows measurements …Read more about
Imaging motile behavior in microfabricated environments One of the major …Read more about
The use of fluorescent proteins such as GFP allows for …Read more about
A quantitative understanding of organism-level behaviour requires predictive models that …Read more about
We have developed an imaging experiment capable of simultaneously obtaining …Read more about
What makes ecosystems stable or fragile? What prevents one species …Read more about
Most of our knowledge about gene regulatory networks has been …Read more about